Year: 2001
Type: dissertation
Abstract: Analysis of variance Apo Apolipoprotein AUC Area under curve AUIC Area under incremental curve BMI Body mass index CETP Cholesteryl ester transfer protein d Density GLC Gas-liquid chromatography HDL High-density lipoprotein HMG-CoA 3-hydroxy-3-methylglutaryl coenzyme A HPLC High-pressure liquid chromatography HSPG Heparan sulphate proteoglycan IDL Intermediate-density lipoprotein LCAT Lecithin:cholesterol acyltransferase LDL Low-density lipoprotein LPL Lipoprotein lipase LRP LDL receptor-related protein PLTP Phospholipid transfer protein SR-BI Scavenger receptor class B type I VLDL Very low-density lipoprotein ABSTRACTSqualene, a non-steroid obligate precursor of cholesterol, is derived from both de novo synthesis from acetyl coenzyme A and from diet.Little is known of the postprandial metabolism of squalene.However, recent evidence exists that squalene may play a role in the development of atherosclerosis such that the removal of postprandial squalene was retarded in women with coronary artery disease.Accordingly, the kinetics and metabolism of squalene in the postprandial state and after intravenous administration in humans were studied.
Source: Työväentutkimus Vuosikirja
Author: Heikki Relas
Language: English
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2159326742