Work

Molecular, cellular, and physiological responses to phosphatidic acid formation in plants

Year: 2011

Type: review

Abstract: Phosphatidic acid (PA) is an essential phospholipid involved in membrane biosynthesis and signal transduction in all eukaryotes. This review focuses on its role as lipid second messenger during plant stress, metabolism, and development. The contribution of different individual isoforms of enzymes that generate and break down PA will be discussed and the downstream responses highlighted, with particular focus on proteins that bind PA. Through characterization of several of these PA targets, a molecular and genetic basis for PA's role in plant stress and development is emerging.

Source: Journal of Experimental Botany

DOI: 10.1093/jxb/err079

Authors: C. Testerink, T. Munnik

Institution: University of Amsterdam

Language: English

Topic: Lipid metabolism and biosynthesis

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funder: Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Awards: Modulation of protein kinase function by the lipid second messenger phosphatidic acid, Novel salt stress-induced signals that control the direction of plant root growth, Sensing the lipid second messenger, phosphatidic acid