Work

Inhibition of pancreatic secretion in man by cigarette smoking

Year: 1972

Type: article

Abstract: Cigarette smoking has been linked to an elevated incidence of duodenal ulcer disease in smokers, although the mechanism is unclear. In 23 young normal subjects single or double secretin tests were performed during non-smoking and smoking periods. Cigarette smoking inhibited the secretion of pancreatic juice and bicarbonate in light smokers (< one pack/day for < three years). Heavy smokers (> one pack/day for > three years) exhibited depressed pancreatic secretory rates during non-smoking periods. Inhibition of pancreatic alkaline secretion by cigarette smoking could be the link between the habit and duodenal ulcer disease.

Source: Gut

DOI: 10.1136/gut.13.5.361

Authors: T. E. Bynum, Travis E. Solomon, Leonard R. Johnson, Eugene D. Jacobson

Institutions: Texas Medical Center, Baylor College of Medicine, University of Oklahoma Medical Center

Language: English

Topic: Helicobacter pylori-related gastroenterology studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2160760264