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Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

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Year: 2013
Type: article
Source: Leukemia
DOI: 10.1038/leu.2013.204
Authors: J A Oyer, X Huang, Y Zheng, J Shim, T Ezponda, Z Carpenter, M Allegretta, C I Okot-Kotber, J P Patel, A Melnick, R L Levine, A Ferrando, A D MacKerell, N L Kelleher, J D Licht, R Popovic
Institutions: Northwestern University, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, University of Maryland, Baltimore, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Columbia University Irving Medical Center, Columbia University, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine
Language: English

Topic: Epigenetics and DNA Methylation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute
Awards: G157389813, G3141316379, G478879025, Cancer Center Support Grant, The Robert H. Lurie Comprehensive Cancer Center
OpenAlex ID: W2160796968
FWCI: 5.378
Cites: 15
Cited by: 145
Related to: 10
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