Work

For Breast Cancer Prognosis, Immunoglobulin Kappa Chain Surfaces to the Top

Year: 2012

Type: article

Abstract: The stromal immunoglobulin kappa chain (IGKC) has been validated as an immunologic biomarker of prognosis and response to therapy in human breast cancer and other cancers. This validation emphasizes the key role of humoral immunity in control of cancer progression and has major implications for determining prognosis of patients with cancer.

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-12-0566

Authors: Theresa L. Whiteside, Soldano Ferrone

Institutions: University of Pittsburgh, UPMC Hillman Cancer Center

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute