Work

The Core and Most Useful Molecules in Organic Chemistry

Year: 2006

Type: article

Abstract: The fruitful core: Organic syntheses reported in the literature from 1850 to 2004 are analyzed with mathematical tools from network theory and statistical physics. There is a set of substances (the core) from which the majority of other organic compounds can be made (see picture; red: core, blue: periphery, green: islands). Search algorithms are used to identify small optimal sets of maximally useful chemicals.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200600881

Authors: Kyle J. M. Bishop, Rafal Klajn, Bartosz A. Grzybowski

Institution: Northwestern University

Language: English

Topic: History and advancements in chemistry

Subfield: Physical and Theoretical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funder: National Science Foundation

Award: G6671297155