Work

The Expanding World of Methylotrophic Metabolism

Year: 2009

Type: review

Abstract: In the past few years, the field of methylotrophy has undergone a significant transformation in terms of discovery of novel types of methylotrophs, novel modes of methylotrophy, and novel metabolic pathways. This time has also been marked by the resolution of long-standing questions regarding methylotrophy and the challenge of long-standing dogmas. This chapter is not intended to provide a comprehensive review of metabolism of methylotrophic bacteria. Instead we focus on significant recent discoveries that are both refining and transforming the current understanding of methylotrophy as a metabolic phenomenon. We also review new directions in methylotroph ecology that improve our understanding of the role of methylotrophy in global biogeochemical processes, along with an outlook for the future challenges in the field.

Source: Annual Review of Microbiology

DOI: 10.1146/annurev.micro.091208.073600

Authors: Ludmila Chistoserdova, Marina G. Kalyuzhnaya, Mary E. Lidstrom

Institution: University of Washington

Language: English

Topic: Microbial metabolism and enzyme function

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Integrated Metabolism in Methylobacterium extroquens AM1