Work

Cryopreservation of hematopoietic stem cells

Year: 2007

Type: review

Abstract: Stem cell transplantation represents a critical approach for the treatment of many malignant and non-malignant diseases. The foundation for these approaches is the ability to cryopreserve marrow cells for future use. This technique is routinely employed in all autologous settings and is critical for cord blood transplantation. A variety of cryopreservatives have been used with multiple freezing and thawing techniques as outlined in the later chapters. Freezing efficiency has been proven repeatedly and the ability of long-term stored marrow to repopulate has been established. Standard approaches outlined here are used in many labs as the field continues to evolve.

Source: American Journal of Hematology

DOI: 10.1002/ajh.20707

Authors: David Berz, Elise M. McCormack, Eric S. Winer, Gerald A. Colvin, Peter J. Quesenberry

Institution: Roger Williams Medical Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Research Resources