Work

Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals

Year: 2013

Type: article

Abstract: The sequence of guinea pig cytomegalovirus (GPCMV) was determined by direct sequencing of salivary gland homogenates obtained following sustained, serial in vivo passage of pathogenic virus in guinea pigs. The 233,501-nucleotide salivary gland (SG) genome was noted to have 11 differences compared to the tissue culture-passaged virus, although no variations were noted in putative protein coding sequences.

Source: Genome Announcements

DOI: 10.1128/genomea.00054-13

Authors: Dongmei Yang, Kristen Tamburro, Dirk Dittmer, Xiaohong Cui, Michael A. McVoy, Nelmary Hernandez-Alvarado, Mark R. Schleiss

Institutions: University of North Carolina at Chapel Hill, Virginia Commonwealth University, Virginia Commonwealth University Medical Center, University of Minnesota

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: NRSA in Genetics, Viral immunomodulation and rational CMV vaccine design, G809027049, G9000157298, Viral Oncogenesis, Latency, and Replication

OpenAlex ID: W2162108535

FWCI: 1.512

Cites: 7

Cited by: 22

Related to: 10