Zależność między poablacyjnymi zmianami wskaźników uszkodzenia miokardium i parametrami ablacji RF
Year: 2005
Type: article
Study design: Observational Study
Abstract: Background: The estimation of postablative injury markers: creatine kinase (CK), it's isoenzyme CK-MB, aspartate aminotransferase (GOT), alanine aminotransferase (GPT), troponine I, myoglobin changes, and their correlation with RF ablation parameters.Material and methods: One hundred eight patients (62 females, 46 males) aged 50.2, range 16-78, who underwent successful ablation (of AV junction 24, AVNRT 33, WPW B 13, WPW A 20, premature ventricular contractions from RVOT 8, atrial flutter 5, other 2).The marker levels were measured before and 20 hours after RF ablation.Results: The mean technical ablation parameters: applications number 10.3, cumulative RF energy 23 139 J. Ablations of a-v junction required lowest applications number and energy, meanwhile those of right-sided Kent bundle the highest applications number.The biggest cumulative energy RF were delivered in WPW A and complex cases.We noted statistically significant postablative increase of troponin I and myoglobin, less significant of GOT and CK.GPT and CK-MB tended to decrease.The correlation between troponin I and myoglobin rise and ablation parameters appeared to be high.Conclusion: Troponin I, myoglobin, and to some extent CK and GOT are potentially clinically useful indicators of minor cardiac injury.(Folia Cardiol.2005; 12: 692-698) cardiac injury markers, troponin I, myoglobin, RF ablation Wstęp Od 1985 r., gdy Huang i wsp.wykonali pierwszą ablację, zaczęto publikować doniesienia na temat mechanizmów powstawania strefy uszkodzenia mięśnia sercowego [1, 2].Szczegółowo zbadano i opisano patofizjologiczne aspekty tworzenia się tej strefy podczas ablacji prądem o częstotliwości fal radiowych (RF, radiofrequency) [3, 4].Stwierdzono, że
Source: Via Medica Journals
Institution: Jagiellonian University
Language: Polish
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2162728553