Work

Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface

Year: 2012

Type: review

Abstract: Biomaterial-associated infections occur on both permanent implants and temporary devices for restoration or support of human functions. Despite increasing use of biomaterials in an aging society, comparatively few biomaterials have been designed that effectively reduce the incidence of biomaterial-associated infections. This review provides design guidelines for infection-reducing strategies based on the concept that the fate of biomaterial implants or devices is a competition between host tissue cell integration and bacterial colonization at their surfaces.

Source: Science Translational Medicine

DOI: 10.1126/scitranslmed.3004528

Authors: Henk J. Busscher, Henny C. van der Mei, Guruprakash Subbiahdoss, Paul C. Jutte, Jan J. A. M. van den Dungen, Sebastian A. J. Zaat, Marcus J. Schultz, David W. Grainger

Institutions: University Medical Center Groningen, University of Groningen, Amsterdam UMC Location University of Amsterdam, University of Amsterdam, University of Utah

Language: English

Topic: Orthopedic Infections and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2162742345

FWCI: 7.278

Cites: 99

Cited by: 721

Related to: 10