Work

Inactivation of viruses with a very low power visible femtosecond laser

Year: 2007

Type: article

Abstract: We demonstrate for the first time that, by using a visible femtosecond laser, it is effective to inactivate viruses such as bacteriophage M13 through impulsive stimulated Raman scattering. By using a very low power visible femtosecond laser having a wavelength of 425 nm and a pulse width of 100 fs, we show that M13 phages were inactivated when the laser power density was greater than or equal to 50 MW cm −2 . The inactivation of M13 phages was determined by plaque counts and depended on the pulse width as well as power density of the excitation laser.

Source: Journal of Physics Condensed Matter

DOI: 10.1088/0953-8984/19/32/322102

Authors: K T Tsen, Shaw-Wei D Tsen, Chih-Long Chang, Chien-Fu Hung, T-C Wu, Juliann G Kiang

Institutions: Arizona State University, Johns Hopkins University, Johns Hopkins Medicine, Uniformed Services University of the Health Sciences

Language: English

Topic: Laser Material Processing Techniques

Subfield: Computational Mechanics

Field: Engineering

Domain: Physical Sciences

Open Access status: bronze

Funders: National Science Foundation, U.S. Department of Defense, Uniformed Services University of the Health Sciences, Division of Materials Research

Award: Optical Studies of High-field Electron and Hole Transport in Nitride-based Wide Bandgap Semiconductor Nanostructures