Work

Choosing anatomical-prior strength for MAP SPECT reconstruction to maximize lesion detectability

Year: 2007

Type: conference-paper

Abstract: With the widespread availability of SPECT/CT systems it has become feasible to incorporate prior knowledge about anatomical boundaries into the SPECT reconstruction process, thus improving observer performance on tasks of clinical interest. We determine the optimal anatomical-prior strength for lesion search by measuring area under the LROC curve using human observers. We conclude that prior strength should be chosen assuming that only organ boundaries are available, even if lesion boundaries will also be known some of the time. We also test whether or not the presence of anatomical priors affects the observer's strategy, and conclude that mixing images with and without priors does not hurt reader performance when priors are not available. Finally, we examine whether using an anatomical prior in SPECT reconstruction helps observer performance when the observer already knows the possible lesion location, and conclude for this task anatomical priors do not provide the same improvement seen in search tasks.

Source: IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

DOI: 10.1109/nssmic.2007.4437049

Authors: Andre Lehovich, Howard C. Gifford, Peter B. Schneider, Michael A. King

Institution: University of Massachusetts Chan Medical School

Language: English

Topic: Medical Imaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Biomedical Imaging and Bioengineering