A Role for A-to-I RNA Editing in Temperature Adaptation
Year: 2012
Type: review
Abstract: A-to-I RNA editing can recode mRNAs, giving organisms the option to express diverse, functionally distinct protein isoforms. Here, we propose that RNA editing is inherently geared for temperature adaptation because it tends to recode to smaller, less stabilizing amino acids. Studies on how editing affects protein function support this idea.
Source: Physiology
Authors: Sandra C. Garrett, Joshua J. C. Rosenthal
Institution: University of Puerto Rico, Medical Sciences Campus
Language: English
Topic: RNA regulation and disease
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2163788272