Work

Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes

Year: 2009

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.1531

Authors: Daniel A Bachovchin, Steven J Brown, Hugh Rosen, Benjamin F Cravatt

Institution: Scripps Research Institute

Language: English

Topic: Enzyme function and inhibition

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, National Institutes of Health, National Institute of Mental Health, National Cancer Institute

Awards: The Comprehensive Center for Chemical Probe Discovery and Optimization at Scripps, G347595984, G3510558551, G6296143508, G6838120957, G762420777, Molecular Libraries Screening Centers Network (MLSCN)(RMI)

OpenAlex ID: W2163824404

FWCI: 8.157

Cites: 51

Cited by: 245

Related to: 10