Work

3D-printed devices for continuous-flow organic chemistry

Year: 2013

Type: article

Abstract: We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with in-line, real-time analysis using an ATR-IR flow cell. As a proof of concept, we utilized two types of organic reactions, imine syntheses and imine reductions, to show how different reactor configurations and substrates give different products.

Source: Beilstein Journal of Organic Chemistry

DOI: 10.3762/bjoc.9.109

Authors: Vincenza Dragone, Victor Sans, Mali H Rosnes, Philip J Kitson, Leroy Cronin

Institution: University of Glasgow

Language: English

Topic: Innovative Microfluidic and Catalytic Techniques Innovation

Subfield: Fluid Flow and Transfer Processes

Field: Chemical Engineering

Domain: Physical Sciences

Open Access status: diamond

Funders: Leverhulme Trust, Royal Society, University of Glasgow, Engineering and Physical Sciences Research Council

Awards: EPSRC Centre for Innovative Manufacturing for Continuous Manufacturing and Crystallisation, The EmergeNET: Towards a Unifying Investigation in Emergence, Emergent Phenomena and Complexity