Work

Extraction of intrinsic fluorescence from single fiber fluorescence measurements on a turbid medium

Year: 2012

Type: article

Abstract: This study utilizes Monte Carlo simulations of single fiber fluorescence to develop an empirical model that corrects for the influence of scattering and absorption on fluorescence intensity (F(SF)). The model expresses F(SF) in terms of the reduced scattering coefficient (μs') and absorption coefficient (μ(a)), each determined independently at excitation and emission wavelengths (λ(x) and λ(m)), and the fiber diameter (d(f)). This model returns accurate descriptions (mean residual <6%) of F(SF) across a biologically relevant range of μs' and μ(a) values and is insensitive to the form of the scattering phase function.

Source: Optics Letters

DOI: 10.1364/ol.37.000948

Authors: Stephen C. Kanick, Dominic J. Robinson, Henricus J. C. M. Sterenborg, Arjen Amelink

Institution: Erasmus MC

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

OpenAlex ID: W2164154303

FWCI: 4.345

Cites: 11

Cited by: 31

Related to: 10