Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel
Year: 2015
Type: article
Abstract: Dental enamel has evolved to resist the most grueling conditions of mechanical stress, fatigue, and wear. Adding insult to injury, it is exposed to the frequently corrosive environment of the oral cavity. While its hierarchical structure is unrivaled in its mechanical resilience, heterogeneity in the distribution of magnesium ions and the presence of Mg-substituted amorphous calcium phosphate (Mg-ACP) as an intergranular phase have recently been shown to increase the susceptibility of mouse enamel to acid attack. Herein we investigate the distribution of two important constituents of enamel, residual organic matter and inorganic carbonate. We find that organics, carbonate, and possibly water show distinct distribution patterns in the mouse enamel crystallites, at simple grain boundaries, and in the amorphous interphase at multiple grain boundaries. This has implications for the resistance to acid corrosion, mechanical properties, and the mechanism by which enamel crystals grow during amelogenesis.
Source: Frontiers in Physiology
Authors: Lyle M. Gordon, Derk Joester
Institution: Northwestern University
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
Funders: National Science Foundation, W. M. Keck Foundation, Northwestern University, Materials Research Science and Engineering Center, Harvard University, International Institute for Nanotechnology, Northwestern University, Office of Naval Research, National Cancer Institute, Division of Materials Research
Awards: G1363675917, G1382933278, G1921142128, Bioengineering Single Crystal Growth, G2379832748, G2506509316, G2598966925, G318734614, G5633509676, G6066762027, G6125965842, G6457034350, MRI: Acquisition of a Local-Electrode Atom-Probe (LEAP) Microscope (An Atom-Probe Tomograph) For Three-Dimensional Nanoscale Characterization of Materials, G6894525921, G7026347881, G7178204, EAGER: Towards Atomic-Scale Imaging of Hybrid Nanomaterials, Bioengineering Single Crystal Growth, CEMRI: Multifunctional Nanoscale Material Structures, Nanoscale Science & Engineering Center for Integrated Nanopatterning and Detection Technologies, G8445745868, G8876996369, The Robert H. Lurie Comprehensive Cancer Center
OpenAlex ID: W2164331388