Work

Biomarkers of HIV Susceptibility and Disease Progression

Year: 2014

Type: article

Abstract: Both host and viral factors are associated with HIV-1 susceptibility and disease progression. Host factors can typically be divided into three categories (Chatterjee, 2010): 1) genes encoding cell-surface receptors or ligands for these proteins, including the classic CCR5 32-bp deletion; 2) genes within the human leukocyte antigens (HLA) that regulate host responses to infection; and 3) other cytokine and immune response genes, including the homozygosity at position −308 in the TNF-alpha promoter.

Source: EBioMedicine

DOI: 10.1016/j.ebiom.2014.11.003

Authors: Vanessa Pirrone, Joshua Mell, Benjamin Janto, Brian Wigdahl

Institution: Drexel University

Language: English

Topic: HIV Research and Treatment

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,780