Work

Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension

Year: 2002

Type: review

Abstract: Accumulating evidence suggests that stellate cells are involved in the regulation of the liver microcirculation and portal hypertension. Activated hepatic stellate cells have the necessary machinery to contract or relax in response to a number of vasoactive substances. Because stellate cells play a role in both fibrosis and portal hypertension, they are currently regarded as therapeutic targets to prevent and treat the complications of chronic liver disease.

Source: Gut

DOI: 10.1136/gut.50.4.571

Authors: H Reynaert, M G Thompson, T Thomas, A Geerts

Institutions: Vrije Universiteit Brussel, Newcastle University

Language: English

Topic: Liver physiology and pathology

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2164864100