More Effective Nanomedicines through Particle Design
Year: 2011
Type: article
Abstract: Nanomedicine is an emerging field that applies concepts in nanotechnology to develop novel diagnostics and therapies. Physical and chemical properties of particles, including size, shape, modulus, surface charge and surface chemistry, play an important role in determining particle-cell interactions, cellular trafficking mechanisms, biodistribution, and pharmacokinetics. This discussion focuses on both nanoparticles and microparticles since microparticles can also provide many insights for the development of drug carriers and possess advantages over nanoparticles in certain applications. This review covers recent major advancement in the nanomedicine field and also highlights studies using the PRINT technology.
Source: Small
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
Awards: G1192852400, Carolina Center of Cancer Nanotechnology Excellence, G1914524142, The Pharmacodynamics of Genes and Oligonucleotides, Delivery of Biological Therapeutics: Using Engineered Particles and Novel Deliver, G2769715519, Carolina Center of Cancer Nanotechnology Excellence, G6594814166, Red Blood Cell Mimics, G7468724011, Biomimetic Approach to the Fabrication of Red Blood Cell Mimics, Engineered Organic Particles of Controlled Size, Shape and Surface Chemistry for
OpenAlex ID: W2165031969