Work

Rescue of vaccinia virus lacking the E3L gene by mutants of E3L

Year: 1995

Type: article

Abstract: Vaccinia virus with the E3L gene deleted was able to replicate in RK-13 but not HeLa cells. This host range phenotype could be complemented by an E3L gene expressed transiently from a plasmid. Analysis of mutants of E3L indicates that the ability to complement deletion of E3L correlates with the ability of mutated proteins to bind double-stranded RNA but not with their ability to migrate to the nucleus.

Source: Journal of Virology

DOI: 10.1128/jvi.69.10.6605-6608.1995

Authors: H W Chang, L H Uribe, B L Jacobs

Institution: Arizona State University

Language: English

Topic: Poxvirus research and outbreaks

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute