Year: 2004
Type: article
Abstract: PURPOSE: Valproate (VPA) is used widely for the treatment of epilepsy but has been associated with hyperandrogenism, hyperinsulinemia, and dyslipidemia. The mechanism for these associations is unknown, but they have been hypothesized to be secondary to VPAassociated weight gain. This study was conducted to test the hypothesis that the antiepileptic drug (AED) lamotrigine (LTG), which also has a broad spectrum of antiseizure efficacy, would not be associated with endocrine abnormalities and would not cause weight gain.
Author: Cynthia L. Harden
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2165555074