Relationship Between Bmi and Severity of Coronary Artery Disease in Female Population of Pakistani Origin
Year: 2012
Type: article
Study design: Observational Study
Abstract: Objective: To assess relationship between BMI and severity of coronary artery disease in femalepopulation of Pakistani origin.Design: Cross sectional observational study.Place and Duration of Study: Armed Forces Institute of Cardiology – National Institute of HeartDiseases (AFIC-NIHD), 1st February 2010 to 31st August 2010Patients and Methods: The study population included 132 female patients undergoing coronaryangiography. Obesity was classified according to the BMI using the National Institutes of Health(NIH) criteria as Normal (BMI 21–24 kg/m2), overweight (BMI 25–29 kg/m2), obesity class I (BMI30–34 kg/m2), Obesity class II (BMI 35 to 39 kg/m2 and obesity class III (BMI 40 or above kg/m2).Coronary angiography data were obtained from the Siemens Queries software system, whichmaintains the database including detailed angiographic findings of all patients at this institution.Significant lesions were defined as those with >70% diameter narrowing of coronary arteries(>50% for the left main coronary artery). We attempted to quantify the “severity of CAD” byascertaining the prevalence of high-risk coronary anatomy (HRCA, defined as >50% stenosis of theleft main coronary artery and/or significant three-vessel coronary artery disease).Results: Comparing overall obese (BMI ≥ 30) vs. non obese groups, a statistically significant lowprevalence of HRCA was encountered in the obese group (26 of 56, 46.4% vs. 54 of 76, 79.5% p <0.05)Conclusion: We concluded that obesity is associated with less severe coronary artery disease inwomen population of Pakistani origin.
Source: Pakistan Heart Journal
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2165815616