Year: 2013
Type: article
Abstract: Despite intensive research efforts for more than 60 years, utilizing diverse vaccine strategies, a safe and efficacious vaccine against shigellosis is not available yet. We are currently witnessing innovative approaches based on elucidation of the virulence mechanisms of Shigella, understanding the immune response to the pathogen and progress in molecular technology for developing Shigella vaccines. It is hoped that these will lead to a licensed effective Shigella vaccine to protect humans against the significant worldwide morbidity and mortality caused by this microorganism.
Source: Therapeutic Advances in Vaccines
Authors: Shai Ashkenazi, Dani Cohen
Institutions: Schneider Children's Medical Center, Tel Aviv University
Language: English
Subfield: Endocrinology
Domain: Life Sciences
Open Access status: bronze
Funder: European Commission
OpenAlex ID: W2165979400