Delivery of Short Hairpin RNA Sequences by Using a Replication-Competent Avian Retroviral Vector
Year: 2004
Type: article
Abstract: While recent studies have demonstrated that retroviral vectors can be used to stably express short hairpin RNA (shRNA) to inhibit gene expression, these studies have utilized replication-defective retroviruses. We describe the creation of a replication-competent, Gateway-compatible retroviral vector capable of expressing shRNA that inhibits the expression of specific genes.
Source: Journal of Virology
Institution: Van Andel Institute
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2166545765