Work

Glycerolipid Biosynthesis in Peroxisomes Via the Acyl Dihydroxyacetone Phosphate Pathway*

Year: 1982

Type: article

Abstract: In recent years, acyl dihydroxyacetone phosphate [acyl-DHAPt) has been shown to be a precursor of glycerolipids and glycerol-ether lipids.'. ' Acyl-DHAP was discovered as a rapidly labeled lipid that was formed in crude mitochondrial fraction from 3'Pi or y-32P[ATP].3 This rapid labeling was due to the enzymatic dephosphorylation and rephosphorylation of endogenous acyl-DHAP present in the crude mitochondrial fraction (equation 1): Acyl-DHAP 2-/- Acyl-DHA (1) ADP ATP Acyl-DHAP was later shown to be biosynthesized by a direct acylation of DHAP with acyl-CoA. catalyzed by DHAP acyltransferase (EC 2.3.1.42) (equation

Source: Annals of the New York Academy of Sciences

DOI: 10.1111/j.1749-6632.1982.tb21415.x

Authors: Amiya K. Hajra, James E. Bishop

Institution: University of Michigan

Language: English

Topic: Lipid metabolism and biosynthesis

Subfield: Biochemistry

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2167428799

FWCI: 8.214

Cites: 41

Cited by: 344

Related to: 10