Work

One Allele's Loss Is Another's Gain: Alterations of NKX2–8 in Non–Small Cell Lung Cancer

Year: 2010

Type: article

Abstract: Large-scale genetic changes such as loss or gain of chromosomes are important drivers of solid tumor carcinogenesis. Recent technological advances in genomic profiling have allowed quantitative detection of gene copy numbers, leading to identification of the 14q13.3 gene locus as functionally important in non-small cell lung cancers.

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-10-3081

Authors: Joel W. Neal, Alice T. Shaw

Institutions: Harvard University, Massachusetts General Hospital, Stanford University

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Cancer Institute