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No xenotropic murine leukemia virus-related virus(XMRV) detected in Swedish monozygotic twinsdiscordant for chronic fatigue

Year: 2011

Type: article

Abstract: The recent debate regarding the possible involvement of xenotropic murine leukemia virus-related virus (XMRV) in chronic fatigue syndrome (CFS) in humans has been intense due to the conflicting results from different studies and the unclear origin of the XMRV virus. In this study, we have addressed this issue by screening 47 pairs of monozygotic twins discordant for CFS using a sensitive PCR assay. The results are clearly negative for all samples. This is consistent with studies showing no evidence for the involvement of XMRV in CFS and supports the possibility that previous positive studies could be caused by laboratory artifacts. Key words: Chronic fatigue syndrome (CFS), idiopathic chronic fatigue, infectious disease, xenotropic murine leukemia virus-related virus (XMRV), monozygotic twins

Source: Journal of General and Molecular Virology

DOI: 10.5897/jgmv.9000015

Authors: Patrick F. Sullivan, Franzcp, Tobias All, er, Cecilia Lindau, Kristina Fahl, reas Jacks, Birgitta Evengaring, Rd, Nancy L. Pedersen, Bjouml, ersson

Language: English

Topic: Fibromyalgia and Chronic Fatigue Syndrome Research

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2168001421

FWCI:

Cites: 20

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Related to: 10