Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display
Year: 2013
Type: article
Abstract: We have developed a novel miniature integrated optical coherence tomography (OCT)-intravascular ultrasound (IVUS) probe, with a 1.5-mm-long rigid part and 0.9-mm outer diameter, for real-time intracoronary imaging of atherosclerotic plaques and guiding of interventional procedures. By placing the OCT ball lens and IVUS transducer back-to-back at the same axial position, this probe can provide automatically coregistered, coaxial OCT-IVUS imaging. To demonstrate its real-time capability, three-dimensional OCT-IVUS imaging of a pig's coronary artery displaying in polar coordinates, as well as images of three major types of atherosclerotic plaques in human cadaver coronary segments, were obtained using this probe and our upgraded system. Histology validation is also presented.
Source: Journal of Biomedical Optics
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
Awards: Integrated multi-modality intravascular US/OCT imaging system, A Resource on Medical Ultrasonic Transducer Technology, Elastographic Imaging of the Retina/Choroid in Age-Related Macular Degeneration, G414091196, A Laser Microbeam Biotechnology Resource, Modeling the Pediatric Upper Airway using A-OCT and Computational Fluid Dynamics, Mechanisms of lens growth regulation, A Laser Microbeam Biotechnology Resource, G9000376361
OpenAlex ID: W2168065825