Work

No difference in leprosy treatment outcomes comparing 12- and 24-dose multidrug regimens: a preliminary study

Year: 2007

Type: article

Abstract: A comparative study was performed on the initial and final bacillary indexes of 213 multibacillary leprosy patients who received 12 doses (Group 1: 128 patients) or 24 doses (Group 2: 85 patients) of multidrug therapy (MDT/WHO) to measure the effectiveness of the two regimens. All patients were evaluated at treatment baseline, 12 months, and 24 months. The reduction in bacillary levels and mean bacillary indexes at 24 months was similar in the two groups. No statistical difference in reaction rates was observed between the two treatment regimens.

Source: Cadernos de Saúde Pública

DOI: 10.1590/s0102-311x2007000400009

Authors: Anna Maria Sales, Paulo Chagastelles Sabroza, José Augusto da Costa Nery, Nádia Cristina Dupprè, Euzenir Nunes Sarno

Institutions: Fundação Oswaldo Cruz, Escola Nacional de Saúde Pública

Language: English

Topic: Leprosy Research and Treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2168478177

FWCI: 0.393

Cites: 16

Cited by: 9

Related to: 10