Relationships between Menopausal and Mood Symptoms and EEG Sleep Measures in a Multi-ethnic Sample of Middle-Aged Women: The SWAN Sleep Study
Year: 2011
Type: article
Study design: Observational Study
Abstract: STUDY OBJECTIVES: Examine associations of vasomotor and mood symptoms with visually scored and computer-generated measures of EEG sleep. DESIGN: Cross-sectional analysis. SETTING: Community-based in-home polysomnography (PSG). PARTICIPANTS: 343 African American, Caucasian, and Chinese women; ages 48-58 years; pre-, peri- or post-menopausal; participating in the Study of Women's Health Across the Nation Sleep Study (SWAN Sleep Study). INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Measures included PSG-assessed sleep duration, continuity, and architecture, delta sleep ratio (DSR) computed from automated counts of delta wave activity, daily diary-assessed vasomotor symptoms (VMS), questionnaires to collect mood (depression, anxiety) symptoms, medication, and lifestyle information, and menopausal status using bleeding criteria. Sleep outcomes were modeled using linear regression. Nocturnal VMS were associated with longer sleep time. Higher anxiety symptom scores were associated with longer sleep latency and lower sleep efficiency, but only in women reporting nocturnal VMS. Contrary to expectations, VMS and mood symptoms were unrelated to either DSR or REM latency. CONCLUSIONS: Vasomotor symptoms moderated associations of anxiety with EEG sleep measures of sleep latency and sleep efficiency and was associated with longer sleep duration in this multi-ethnic sample of midlife women.
Source: SLEEP
DOI: 10.5665/sleep.1244
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Awards: G1078949291, G1395245948, Study of Women's Health Across the Nation (SWAN) V: UCLA Site, Study of Women's Health Across the Nation (SWAN) V: Chicago site, G1650445419, G1694870497, Study of Women's Health Across the Nation (SWAN): New Jersey, G2328791590, G2490884996, G2701036747, G2853426343, G2886598935, Study of Women's Health Across the Nation (SWAN) V: Coordinating Center, University of Pittsburgh Clinical and Translational Science Institute, G4094362930, Study of Women's Health Across the Nation (SWAN) V: Central Laboratory, G4492651742, G4668657675, G4847607846, SWAN Sleep Study II: Pittsburgh, G6423459859, G6454223305, G6683184264, Study of Women's Health Across the Nation (SWAN V): Michigan Site, G6881890559, SWAN Sleep Study II - Michigan Center, Study of Women's Health Across the Nation(SWAN) V: Pittsburgh, SWAN Sleep Study II - Chicago (Rush) Site, G988252460
OpenAlex ID: W2168496971