Work

How complete are current yeast and human protein-interaction networks?

Year: 2006
Type: article
Abstract: We estimate the full yeast protein-protein interaction network to contain 37,800-75,500 interactions and the human network 154,000-369,000, but owing to a high false-positive rate, current maps are roughly only 50% and 10% complete, respectively. Paradoxically, releasing raw, unfiltered assay data might help separate true from false interactions.
Language: English
Open Access status: gold
Estimated APC paid: $5,490
OpenAlex ID: W2168708357
FWCI: 14.67
Cites: 60
Cited by: 402
Related to: 10