Work

Risk factors for white matter changes detected by magnetic resonance imaging in the elderly.

Year: 1990

Type: article

Abstract: We found increased age (p = 0.001) and history or evidence of stroke (p = 0.016) to be significant independent multivariate predictors of the presence and severity of leukoencephalopathy on magnetic resonance imaging brain scans in a mixed population of 35 elderly psychiatric patients and 25 neurologically healthy elderly volunteers. These results suggest that subcortical ischemia, as well as age-related changes that may not be vascular in origin, contribute to the emergence of periventricular and other deep white matter hyperintensities that are commonly seen on the magnetic resonance imaging brain scans of older adults.

Source: Stroke

DOI: 10.1161/01.str.21.10.1424

Authors: P Sullivan, R Pary, F Telang, A H Rifai, G S Zubenko

Institution: University of Pittsburgh

Language: English

Topic: Cerebrovascular and genetic disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institute on Aging, National Institute of Mental Health