Work

Nanofibrous Lipid Membranes Capable of Functionally Immobilizing Antibodies and Capturing Specific Cells

Year: 2011

Type: article

Abstract: Polymerizable cholesteryl-succinyl silane was synthesized and fabricated into stable nanofibrous lipid membranes using a combined sol-gel and electrospinning process. The resulting nanofibrous lipid membranes are capable of functionally immobilizing membrane proteins such as antibodies, thereby enabling targeted cell capture via the antigen-antibody interactions.

Source: Advanced Materials

DOI: 10.1002/adma.201101516

Authors: Zhengbao Zha, Celine Cohn, Zhifei Dai, Weiguo Qiu, Jinhong Zhang, Xiaoyi Wu

Institutions: University of Arizona, BIO5 Institute, Harbin Institute of Technology

Language: English

Topic: Electrospun Nanofibers in Biomedical Applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Heart, Lung, and Blood Institute, National Institute of Biomedical Imaging and Bioengineering