Work

Caudate volume in offspring of patients with schizophrenia

Year: 2007

Type: article

Abstract: Caudate nuclei are smaller in drug-naive people with schizophrenia but larger in antipsychotic-treated patients. In this magnetic resonance imaging study we found volume reduction of right and left caudate by 8.9 and 8.1% respectively in 50 offspring without psychosis of patients with schizophrenia compared with 53 age- and gender-matched controls, providing new evidence that caudate volume reduction may be a trait-related abnormality in schizophrenia.

Source: The British Journal of Psychiatry

DOI: 10.1192/bjp.bp.106.029017

Authors: Rajaprabhakaran Rajarethinam, Ameet Upadhyaya, Pon Tsou, Margie Upadhyaya, Matcheri S. Keshavan

Institutions: Wayne State University, University of Pittsburgh

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze