Year: 2010
Type: review
Abstract: Despite intensive control efforts over the past decades, Brazil still accounts for more than 50% of the malaria burden in the Americas and the Caribbean, with 458,041 slide-confirmed cases reported countrywide in 2007. The reason malaria has proved so difficult to control in this middle-income country with a reasonable health infrastructure remains unclear. Here we examine whether four strategies that were largely successful in other countries (aggressive active case detection, improved anti-relapse therapy for P. vivax infections, distribution of insecticide-treated bed nets, and selective house spraying with residual insecticides) are likely to work in Brazil. We review evidence from field and laboratory studies and identify gaps in our knowledge that require further investigation with well-designed large-scale trials.
DOI: 10.3855/jidc.760
Institutions: Universidade de São Paulo, Universidade Federal do Acre
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $394
Awards: Epidemiologia da malaria: fatores de risco, distribuicao espaco-temporal e resposta ao tratamento em uma coorte rural amazonica., Population structure and transmission dynamics of Plasmodium vivax, Aquisicao de imunidade contra plasmodium vivax: estudo longitudinal em uma comunidade rural da amazonia brasileira.
OpenAlex ID: W2169616600