Work

Effect of Calcineurin Inhibitors on Posaconazole Blood Levels as Measured by the MVista Microbiological Assay

Year: 2007

Type: article

Abstract: Calcineurin inhibitors may augment the effects of antifungal drugs in microbiological assays. We examined this interaction in a microbiological assay for posaconazole. No effect was observed. However, concurrent or recently discontinued treatment with other antifungal drugs caused false-positive results, emphasizing a limitation of microbiological assays for antifungal drug level measurement.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.01096-07

Authors: David Zhuang, Melinda Smedema, Ann LeMonte, Benita K. Book, Mark D. Pescovitz, L. Joseph Wheat

Institutions: Indiana University Indianapolis, Indiana University School of Medicine

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2169688735

FWCI:

Cites: 7

Cited by: 3

Related to: 10