Work

Draft Genome Sequence of Escherichia coli Strain ATCC 23506 (Serovar O10:K5:H4)

Year: 2013

Type: article

Abstract: We report the 5.101-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23506 (serovar O10:K5:H4, also known as NCDC Bi 8337-41) genome. This uropathogenic strain, commonly referred to as E. coli K5, produces N-acetyl heparosan, a glycosaminoglycan-like capsular polysaccharide and precursor to the anticoagulant pharmaceutical heparin. Metabolic reconstruction of this genome will enable the prediction of gene deletions and overexpressions that lead to increased heparosan production.

Source: Genome Announcements

DOI: 10.1128/genomea.00049-13

Authors: Brady F. Cress, Zachary R. Greene, Robert J. Linhardt, Mattheos A. G. Koffas

Institution: Rensselaer Polytechnic Institute

Language: English

Topic: Escherichia coli research studies

Subfield: Endocrinology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Rensselaer Polytechnic Institute, Weill Cornell Medical College