Aging and Bone
Year: 2010
Type: review
Abstract: Bones provide mechanical and protective function, while also serving as housing for marrow and a site for regulation of calcium ion homeostasis. The properties of bones do not remain constant with age; rather, they change throughout life, in some cases improving in function, but in others, function deteriorates. Here we review the modifications in the mechanical function and shape of bones, the bone cells, the matrix they produce, and the mineral that is deposited on this matrix, while presenting recent theories about the factors leading to these changes.
Source: Journal of Dental Research
Authors: A.L. Boskey, R. Coleman
Institution: Hospital for Special Surgery
Language: English
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: MECHANISM OF HARD TISSUE MINERALIZATION, G2853582701, IN VITRO INITIATION OF BIOLOGICAL CALCIFICATION, MECHANISM OF HARD TISSUE MINERALIZATION, Proteoglycan Regulation of Growth Plate Cartilage Calcification, FT-IR Microscopy of Mineral Structure in Osteoporosis, Musculoskeletal Repair and Regeneration
OpenAlex ID: W2169887586