Year: 2008
Type: article
Abstract: OBJECTIVE: While the adverse effect of Major Depressive Episode on role functioning is well established, the exact pathways remain unclear. METHOD: Data from The European Study of the Epidemiology of Mental Disorders, a cross-sectional survey including 21 425 adults from six European countries, were used to assess 12-month depression (Composite International Diagnostic Interview), activity limitations and role functioning in the past 30 days (Disability Assessment Schedule). An a priori model based on the World Health Organization's International Classification of Functioning, Disability and Health was designed and a structural equation model for categorical and ordinal data was used (MPlus) to estimate the extent to which six limitations mediated the association between depression and role functioning. RESULTS: The unadjusted association between depression and role functioning was strong (0.43; SE = 0.04). In the best-fitting model, only concentration and attention problems and embarrassment mediated a significant amount of association (direct effect dropped to 0.17; SE = 0.10, which was no longer significant). CONCLUSIONS: Targeting cognition and embarrassment in treatment could help reduce depression-associated role disfunctioning.
Source: Acta Psychiatrica Scandinavica
Authors: M. A. Buist‐Bouwman, J. Ormel, R. De Graaf, P. De Jonge, E. Van Sonderen, J. Alonso, R. Bruffaerts, W. A. M. Vollebergh, the ESEMeD/MHEDEA 2000 investigators
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funders: John D. and Catherine T. MacArthur Foundation, Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, GlaxoSmithKline, World Health Organization, European Commission, Generalitat de Catalunya, Regione Piemonte, National Institutes of Health, Pfizer Foundation, Pan American Health Organization, Instituto de Salud Carlos III, Departament de Salut, Generalitat de Catalunya, National Institute of Mental Health, National Institute on Drug Abuse, Fogarty International Center
Awards: G1037158725, World Mental Health Consortium Annual Meeting 2003-07, G1550703150, G2237026874, Social Role Disability and Mental-Physical Co-Morbidity, Drug Dependence Epidemiology and Enviromics, G281960396, G2880481365, CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000, G3658001182, G4036403015, G4076321871, G4134838996, G4226508884, G4784666921, Risk Factors for Psychopathology in the WHO WMH Surveys, G5506155316, G578575042, G6629244973, G7284921876, G7433974870, G851565850, Lebanon-Epidemiology: The NCS Replication Study
OpenAlex ID: W2170135777