Work

Acute Lower Respiratory Tract Infection

Year: 2008

Type: review

Abstract: Acute lower respiratory tract infections are a major cause of death and disability, yet the mechanisms that make such infections so virulent are not entirely understood. This review emphasizes the roles of inflammation and the response of the innate immune system and explains how these two processes interact to rid the lung of microbes but also how they can bring the elimination of infection in the lung to a perilous climax.

Source: New England Journal of Medicine

DOI: 10.1056/nejmra074111

Author: Joseph P. Mizgerd

Institution: Harvard University

Language: English

Topic: Immune Response and Inflammation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Heart, Lung, and Blood Institute