Work

Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time

Year: 2011

Type: article

Source: Molecular Pharmacology

DOI: 10.1124/mol.111.074997

Authors: Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J.G. Tesmer, Roger K. Sunahara

Institutions: University of Michigan, Life Sciences Institute

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Drug Abuse, National Institute of General Medical Sciences, Argonne National Laboratory

Awards: G12497175, Development of Esterases for the Treatment of Cocaine Overdose and Abuse, G3374992730, Interdepartmental Training in Pharmacological Sciences, Evaluation in Primates of Cocaine Esterase for the Treatment of Cocaine Toxicity, G4792905505, G5882035118, High-activity mutants of cocaine esterase for treatment of drug addiction

OpenAlex ID: W2170243062

FWCI: 1.167

Cites: 54

Cited by: 22

Related to: 10