Short-term combined exercise training improves the health of HIV-infected patients
Year: 2013
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: This study tested the benefits of combined aerobic and resistance exercise training (CARET) in HIV-infected individuals receiving antiretroviral therapy. Twenty-three human immunodeficiency virus (HIV)-infected men and women, predominantly of lower socioeconomic status (SES), were randomly assigned and completed 12 weeks of: (a) standard medical treatment plus CARET or (b) standard medical treatment only. At baseline and follow-up, immune functioning, metabolic variables, quality of life (QoL), physical characteristics, and physical fitness were measured. The control group showed a significant decrease in CD4+ T cell count (-16%, p<0.05), whereas the exercise group maintained a more stable count after the intervention (-3%, p=0.39). Furthermore, exercise participants showed significant improvements in waist circumference (-2%, p<0.05), fasting glucose (-16%, p<0.05), physical (+11%, p<0.03) and mental (+10%, p<0.02) QoL, estimated VO2max (+21%, p<0.01), upper body strength (+15%, p<0.05), and lower body strength (+22%, p<0.05). Our 12-week, supervised, moderate-intensity CARET program resulted in more stable CD4 count and significant health improvements in HIV-infected individuals of lower SES.
Key words: Antiretroviral therapy, aerobic and resistance exercise training, immune functioning, quality of life.
Source: Journal of AIDS and HIV Research
DOI: 10.5897/jahr12.076
Authors: Eduard Tiozzo, Dushyantha Jayaweera, Allan Rodríguez, Janet Konefal, Angelica B. Melillo, Sarah Adwan, Lawrence R. Chen, Chad Parvus, Miguel Figueroa, Nicole Hodgson, Judi M. Woolger, Ronald Kanka, Arlette C. Perry, John E. Lewis
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2170734126