Work

Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis

Year: 2007

Type: article

Abstract: Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis.

Source: Journal of Clinical Microbiology

DOI: 10.1128/jcm.01729-07

Authors: Andrea Gori, Camilla Tincati, Giuliano Rizzardini, Carlo Torti, Tiziana Quirino, Monique Haarman, Kaouther Ben Amor, Jacqueline van Schaik, Aldwin Vriesema, Jan Knol, Giulia Marchetti, Gjalt Welling, Mario Clerici

Institutions: University of Milan, Ospedale San Paolo, Azienda Ospedaliera San Gerardo, University of Milano-Bicocca, Luigi Sacco Hospital, Ospedale di Circolo di Busto Arsizio, University of Brescia, University Medical Center Groningen, University of Groningen

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2170850530

FWCI: 1.919

Cites: 17

Cited by: 242

Related to: 8