Work

The Context of Blood Vessels and Response to VEGF-Targeted Therapy

Year: 2013

Type: article

Abstract: Although therapy directed against VEGF has produced clinical benefit, an understanding of responsive tumor characteristics is lacking. Blood vessel location relative to tumor cells and stromal factors may influence tumor susceptibility to VEGF-targeted therapy. Clinical validation of this potential biomarker is needed to influence clinical practice.

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-13-2479

Author: Brian I. Rini

Institutions: Cleveland Clinic, Cleveland Clinic Lerner College of Medicine

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2171228060