Work

Stem Cell Transplantation and Long-Term Survival for Primary Immunodeficiencies: Outcomes Among the Donor Sources and Different Diagnostic Groups

Year: 2013

Type: article

Abstract: Matched related hemopoietic stem cell transplantation (MRD-HSCT) for patients with Primary Immunodeficiencies (PIDs) has been life saving. There is less information regarding stem cell transplantation from unrelated donors including umbilical cord blood units. We report the outcome following HSCT (1998-2012) in 69 patients with PIDs: SCID (n=35), WAS (n=9), Phagocytic disorders (CGD (n=17), LAD (n=4)); and other (n=4; one each; Interferon γ receptor deficiency, Hyper IgM syndrome, Autosomal recessive Hyper IgE syndrome (Dock 8 mutation), and reticular dysgenesis).

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2012.11.127