Work

Telencephalon enlargement by the convergent evolution of expanded subventricular zones

Year: 2008

Type: article

Abstract: Some mammals and birds independently evolved an enlarged telencephalon. They appear to have done so, at least in part, by developing a thick telencephalic subventricular zone (SVZ). We suggest that this correlation between telencephalic enlargement and SVZ expansion is due to a mechanical constraint acting on the proliferative ventricular zone (VZ). Essentially, we argue that rapid proliferation in the VZ after post-mitotic cells in the overlying mantle zone have begun to form limits the VZ's tangential expandability and forces some proliferating cells to emigrate from the VZ and expand the pool of proliferating cells that comprise the SVZ.

Source: Biology Letters

DOI: 10.1098/rsbl.2008.0439

Authors: Georg F Striedter, Christine J Charvet

Institution: University of California, Irvine

Language: English

Topic: Neurogenesis and neuroplasticity mechanisms

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, University of California, Irvine

Award: Evolution of Brain Development in Birds