Increased PD-L1 expression in KRAS mutated premalignant human bronchial epithelial cells is enhanced by LKB1 loss and mediated by ERK activation
Year: 2015
Type: article
Abstract: Meeting abstracts PD-1/PD-L1 immune checkpoint pathway mediates tumor evasion from the immune system, and may be associated with poor prognosis in lung cancer. Activating KRAS mutations and LKB1 loss are common mutations in non-small cell lung carcinoma (NSCLC). Patients with mutated KRAS
Authors: Mi-Heon Lee, Jane Yanagawa, Rui Li, Tonya C Walser, Kostyantyn Krysan, Gerald Wang, Jonathan W Goldman, Edward B Garon Garon, Gang Zeng, Sherven Sharma, John D Minna, David Carbone, Steven M Dubinett, Jay M Lee
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2171925209