Work

Rapid Syntheses of Benzopyrans from o-OBOC Salicylaldehydes and Salicyl alcohols: A Three-Component Reaction

Year: 2002

Type: article

Abstract: The Diels-Alder reactions of o-quinone methides generated from OBOC-salicylic aldehydes and alcohols are described, allowing for the synthesis of various substituted benzopyrans. The low temperatures employed for this procedure enable high diastereoselectivity in reactions with beta-substituted o-quinone methides.

Source: The Journal of Organic Chemistry

DOI: 10.1021/jo020224v

Authors: Ryan M. Jones, Carolyn Selenski, Thomas R. R. Pettus

Institution: University of California, Santa Barbara

Language: English

Topic: Multicomponent Synthesis of Heterocycles

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, Division of Chemistry

Awards: G4690600686, The Synthesis and Application of Novel Aromatic Materials